Nicotine Blood Levels and Short-term Smoking Reduction with an Electronic Nicotine Delivery System
Thursday, April 10, 2014
Posted by: Natalia Gromov
Am J Health Behav. 2014
Nicotine Blood Levels
and Short-term Smoking Reduction with an Electronic Nicotine Delivery System
Nides MA, Leischow SJ,
Bhatter M, Simmons M.
This study evaluated nicotine delivery from the NJOY(®) King Bold Electronic
Nicotine Delivery System (ENDS) and its short-term potential for smoking
reduction or cessation. METHODS: One week of ad libitum use was followed by
measurements of plasma nicotine, heart rate, and craving and withdrawal after
12 hours of nicotine abstinence in 25 adult smokers not interested in quitting.
RESULTS: After 5 minutes of use, blood nicotine levels increased by a mean of
3.5 ng/mL (p < .001), heart rate increased, and craving was reduced by 55%.
Cigarettes per day were reduced by 39% during the test week, and perceptions of
use for reduction or cessation were positive. CONCLUSIONS: The NJOY(®) King
Bold ENDS delivers nicotine and led to short-term smoking reduction.