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NAQC Newsroom: Research

Randomised Trial of Two Nicotine Patch Protocols Distributed Through a State Quitline.

Friday, December 12, 2014  
Posted by: Natalia Gromov
Emily K Burns, Nancy E Hood, Emma Goforth, Arnold H Levinson
Randomised Trial of Two Nicotine Patch Protocols Distributed Through a State Quitline.
Overall, 1495 study participants were enrolled and 57.7% completed follow-up. Abstinence rates did not differ significantly between study conditions: 13.8% versus 12.4% in 4-week versus 8-week arms, respectively, (30-day point abstinence, non-respondents treated as smokers). NRT duration was similar in both groups, due in part to purchase of additional patches in the 4-week group. About one-third of the 8-week group requested the full 8-week supply and had higher abstinence rates. Cost per quit was lower in the 4-week (compared to 8-week) group.
A randomised trial did not find worse cessation outcomes among quitline users who received half the minimum recommended course of NRT, but offering the full recommended course using a split-shipment protocol may be reasonably cost-effective and supportive of NRT adherers.

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