The Relations between False Positive and Negative Screens and Smoking Cessation and Relapse in the..
Thursday, July 9, 2015
Posted by: Natalia Gromov
Clark MA, Gorelick JJ, Sicks JD, Park ER, Graham AL, Abrams DB, Gareen IF.
The Relations between False Positive and Negative Screens and Smoking Cessation and Relapse in the National Lung Cancer Screening Trial: Implications for Public Health.
Nicotine Tob Res. 2015 Mar 6. [Epub ahead of print].
Lung screening is an opportunity for smoking cessation and relapse prevention, but smoking behaviors may differ across screening results. Changes in smoking were evaluated among 18,840 current and former smokers, aged 55-74, scheduled to receive three annual lung screenings. Participants were randomized to low-dose CT or single-view chest radiography in the American College of Radiology / National Lung Screening Trial (NLST). During five years of follow-up, annual point prevalence quit rates ranged from 11.6 percent to 13.4 percent. About half (48 percent) of current smokers reported a quit attempt and seven percent of long-term former smokers relapsed. A false positive screen was associated with increased smoking cessation and less relapse among recent quitters. Consistently negative screens were not associated with greater relapse among long-term former smokers. Given that the Affordable Care Act requires most health plans to cover smoking cessation and lung screening, the impact and cost-effectiveness of lung screening could be further enhanced with the addition of smoking cessation interventions.