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NAQC Newsroom: Tobacco Control

Influence of Nicotine Metabolism Genes on Smoking Throughout the Tobacco Use Continuum: From Adolesc

Tuesday, December 01, 2015  
Posted by: Natalia Gromov
Join Dr. Meghan Chenoweth as she hosts a webinar entitled “Influence of Nicotine Metabolism Genes on Smoking Throughout the Tobacco Use Continuum: From Adolescence to Adulthood.” This webinar will cover the influence of genetically variable nicotine metabolism on a variety of smoking phenotypes, from smoking initiation through to cessation and is hosted by SRNT’s Basic Science and Genetics Networks. The impact of variation in CYP2A6 and CYP2B6, which code for key nicotine-metabolizing enzymes, on nicotine metabolism and associations with adolescent and adult smoking behaviors will be described. Animal models developed to explore the mechanisms behind these genetic associations with smoking behaviors will be introduced. Finally, the potential utility of this genetic information in tailoring and optimizing smoking cessation treatments will be discussed.
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