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NAQC Newsroom: Research

Is There Evidence for Potential Harm of Electronic Cigarette Use in Pregnancy?

Friday, December 12, 2014  
Posted by: Natalia Gromov
Suter MA, Mastrobattista J, Sachs M, Aagaard K.
Is There Evidence for Potential Harm of Electronic Cigarette Use in Pregnancy?
Birth Defects Res A Clin Mol Teratol. 2014 Nov 4. doi: 10.1002/bdra.23333. [Epub ahead of print]
In utero nicotine exposure in animal models is associated with adverse effects for the offspring lung, cardiovascular system and brain. In the lung, this included reduced surface area, weight, and volume, as well as emphysema-like lesions. In adulthood, exposed offspring demonstrate elevated blood pressure and increased perivascular adipose tissue. In the brain, exposure alters offspring serotonergic, dopaminergic, and norepinephrine networks, which in turn are associated with behavioral and cognitive impairments. While reviewing the current data on the lack of efficacy of nicotine replacement therapy in pregnant women, and highlight different nicotine containing products such as snuff, snus, and hookah. Study concludes that no amount of nicotine is known to be safe during pregnancy, and studies specifically addressing this risk are crucial and an imminent public health issue. Birth Defects Research (Part A), 2014. © 2014 Wiley Periodicals, Inc.

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