Can e-Cigarettes and Pharmaceutical Aids Increase Smoking Cessation and Reduce Cigarette Consumption
Wednesday, July 18, 2018
Posted by: Natalia Gromov
Benmarhnia T, Pierce JP, Leas E, White MM, Strong DR, Noble ML, Trinidad DR.
Can e-Cigarettes and Pharmaceutical Aids Increase Smoking Cessation and Reduce Cigarette Consumption? Findings from a Nationally Representative Cohort of American Smokers.
Am J Epidemiol. 2018 Jun 27. doi: 10.1093/aje/kwy129. [Epub ahead of print]
Many smokers believe that electronic nicotine delivery systems (ENDS) and pharmaceutical cessation aids can help them quit smoking or reduce cigarette consumption, but the evidence for e-cigarettes to aid quitting is limited. Examining 3,093 quit attempters in the nationally-representative US Population Assessment of Tobacco and Health (PATH) Study between 2013 and 2015, we evaluated the influence of ENDS and pharmaceutical cessation aids on persistent abstinence (≥30 days) from cigarettes, and reduced cigarette consumption, using Propensity Score Matching to balance comparison groups on potential confounders and multiple imputation to handle missing data. At PATH Wave 2, 25.2% of quit attempters reported using ENDS to quit during the previous year, making it the most popular cessation aid in 2014-15. More quit attempters were persistently cigarette abstinent than persistently tobacco abstinent (15.5±0.8% vs 9.6±0.6%). Using ENDS to quit cigarettes increased the probability of persistent cigarette abstinence at Wave 2 (Risk Difference (RD)=6%; 95% CI: 2%;10%), but using approved pharmaceutical aids did not (varenicline RD=2%; 95% CI: -6%,13%; buproprion RD=4%, 95% CI: -6%, 17%; NRT RD=-3%, 95% CI -8%, 2%). Among quit attempters who relapsed, ENDS did not reduce the average daily cigarette consumption (-0.18 cigarettes per day; 95% CI: -1.87;1.51).
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