Adolescents' Use of Nicotine Replacement Therapy for Smoking Cessation: Predictors of Compliance
Wednesday, March 12, 2014
Posted by: Natalia Gromov
Psychopharmacology (Berl).
2014 Mar 5. [Epub ahead of print]
Adolescents' Use of
Nicotine Replacement Therapy for Smoking Cessation: Predictors of Compliance
Trajectories.
Scherphof CS, van den
Eijnden RJ, Lugtig P, Engels RC, Vollebergh WA.
Previous research has shown limited efficacy of nicotine replacement therapy
(NRT) among adolescents and generally low compliance rates. As higher
compliance rates are associated with improved abstinence rates, the present
study examined predictors of NRT compliance. This study aims to test whether
different NRT compliance trajectories can be distinguished among adolescents.
METHODS: Data were used from a randomized controlled trial that tested the
efficacy of nicotine patches versus placebo patches among 265 Dutch
adolescents. During NRT treatment, adolescents filled out six online
questionnaires in which they reported on the number of days they used the
patches. Predictors (i.e., demographic and smoking-related factors and
personality characteristics) and end-of-treatment abstinence were also
administered through these self-reports. Latent class growth analysis (LCGA)
was used to analyze compliance data by classifying individuals into similar
growth trajectories. RESULTS: Three compliance trajectories were found (i.e.,
"compliers" (n = 89), "moderate decreasers" (n = 41), and
"strong decreasers" (n = 127)). The compliers can be characterized by
higher levels of conscientiousness and agreeableness and lower levels of
extraversion compared with the strong decreasers, and by higher levels of
conscientiousness and education compared with the moderate decreasers. Among
the compliers, a substantially higher percentage of adolescents achieved
abstinence at end-of-treatment (10 %) compared with the moderate decreasers (3
%) and the strong decreasers (6 %). CONCLUSIONS: These findings could be the
starting point for person-tailored interventions that aim to enhance NRT
compliance rates among adolescents.
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