Current E-Cigarette Research in the Context of Asthma.
Friday, August 14, 2020
Posted by: Natalia Gromov
Hickman E, Jaspers I.
Current E-Cigarette
Research in the Context of Asthma.
Curr Allergy Asthma Rep. 2020;20(10):62. Published 2020 Aug 8.
doi:10.1007/s11882-020-00952-2
Purpose of review: The
purpose of this review is to integrate recent research on the respiratory
immune effects of e-cigarettes with the pathogenesis of asthma to better
understand how e-cigarettes may affect asthmatics and to note critical
knowledge gaps regarding the effects of e-cigarettes on asthmatics.
Recent findings: Human,
rodent, and cell culture studies show that key cellular functions of epithelial
cells, macrophages, and neutrophils are altered by e-cigarette exposure.
Because respiratory immunity is already dysregulated in asthma, further
alteration of cellular function by e-cigarettes could impact asthma
development, severity, and/or exacerbations. Future research is needed to more
directly investigate this relationship using controlled human exposure studies and
exposure of cell culture or animal models of asthma to e-cigarettes.
|
|
Email to a Friend