Could E-cigarette Vaping Contribute to Heart Disease?
Friday, August 14, 2020
Posted by: Natalia Gromov
Kuntic M, Hahad O, Daiber
A, Münzel T.
Could
E-cigarette Vaping Contribute to Heart Disease?
[published online ahead of print, 2020 Aug 6]. Expert Rev Respir Med. 2020;10.1080/17476348.2020.1807332.
doi:10.1080/17476348.2020.1807332
Introduction: E-cigarettes
have become a controversial topic. While their benefits are questioned by the
scientific community, a part of the medical profession is still supporting them
as an effective harm reduction tool for smoking cessation. The impact of
E-cigarettes on the cardiovascular system is still elusive.
Areas covered: We
assessed results from animal, pre(clinical), and epidemiological studies to
critically evaluate and synthesize evidence relevant to the cardiovascular
effects of E-cigarettes. Animal studies have demonstrated that E-cigarette
vapor exposure can cause endothelial and cardiac dysfunction. However, there
have also been reports on the less harmful effects of E-cigarette vapor
exposure in comparison to classical tobacco cigarettes. Measurements of
flow-mediated dilation in acute human exposure settings have mostly
demonstrated that E-cigarettes cause vascular endothelial dysfunction. Long
term epidemiological studies have shown that E-cigarette use is associated with
an increased risk for cardiovascular disease, although switching from classical
tobacco cigarettes to E-cigarettes can have beneficial cardiovascular effects.
Misinterpretation of scientific data by activists on either side is another
problem.
Expert opinion: In
conclusion, we need more and better (pre)clinical data comparing the health
effects of E-cigarette vaping as compared with tobacco cigarette smoking, in
order to counsel the legislation for better health policies.
Keywords: Electronic
nicotine delivery system; acrolein; cardiovascular disease; endothelial
dysfunction; oxidative stress; vaping.
|
|
Email to a Friend