NAQC Newsroom: Research

Examining E-cigarette Flavor Use and Preference by Menthol Cigarette Status and Quit Duration among

Tuesday, September 16, 2025  
Posted by: Natalia Gromov

Joseph M, Morean ME, Wu R, Krishnan-Sarin S, O'Malley SS, Bold KW.
Examining E-cigarette Flavor Use and Preference by Menthol Cigarette Status and Quit Duration among U.S. Adults Using E-cigarettes in a Smoking Cessation Attempt
Nicotine Tob Res. 2025 Aug 22;27(9):1657-1661. doi: 10.1093/ntr/ntaf059. PMID: 40056399; PMCID: PMC12370470.

Introduction: Switching to e-cigarettes may help some adults quit smoking. More research is needed to understand the role of flavors in e-cigarettes among adults who smoke menthol and non-menthol cigarettes to inform policy and efforts to reduce cigarette use.

Aims and methods: Cross-sectional survey data from adults who used e-cigarettes to quit smoking (N = 857) were used to examine e-cigarette flavors used and preferred during the smoking cessation attempt and differences by cigarette type (menthol vs. non-menthol). A general linear model was used to examine the main effects and interaction of cigarette type (menthol vs. non-menthol) and preferred e-cigarette flavor for quitting on the duration of smoking abstinence.

Results: Adults who smoked menthol cigarettes were more likely to prefer menthol/mint versus tobacco (AOR = 12.29, 95% CI = 7.42 to 20.34) or other e-cigarette flavors (AOR = 7.55, 95% CI = 4.22 to 13.50). However, there was a significant interaction between cigarette type and preferred e-cigarette flavor (p = .01). Adults smoking non-menthol cigarettes who preferred to use menthol/mint flavored e-cigarettes to quit smoking had longer durations of abstinence compared to those preferring tobacco flavor (LSmean difference = 0.92, CI: 0.39 to 1.46) or other flavors (LSmean difference = 0.81, CI: 0.15 to 1.46). Among participants who typically smoked menthol cigarettes, e-cigarette flavor preference was not associated significantly with duration of abstinence (F 3,834 = 1.36, p = .25).

Conclusions: Menthol/mint e-cigarettes are more often preferred by adults who smoke menthol cigarettes, yet preferring menthol/mint e-cigarettes was associated with longer abstinence durations for those who smoke non-menthol (vs. menthol) cigarettes.

Implications: This study provides new information about the types of e-cigarette flavors used and preferred by adults who smoke menthol versus non-menthol cigarettes when using e-cigarettes to try to quit. The association between e-cigarette flavors and abstinence duration varies by cigarette type. While menthol/mint e-cigarette flavors are preferred by adults who smoke menthol cigarettes, menthol/mint e-cigarettes are associated with longer quitting success for those who smoke non-menthol (vs. menthol) cigarettes. More research is needed to understand the impact of e-cigarette flavor by cigarette type. These results may help inform tobacco policy and efforts to maximize reductions in cigarette use.